Endocrine Abstracts

In all probability, a thesis is the longest single document that anyone is likely to write as a scientist. It requires much planning to ensure that the thesis gets written and submitted on time. To begin with, plan the overall outline of the thesis. With some variation, most theses begin with a comprehensive introduction/literature review. A chapter describing the materials and methods invariably follows. The subsequent chapters contain the material you have sweated over i.e. ...

Polyunsaturated fatty acids (PUFA) act as precursors for prostaglandin (PG) synthesis. PGs both inhibit and stimulate ovarian steroidogenesis. We have therefore examined the hypothesis that high n-3 PUFA diets affect ovarian steroid synthesis through modulating prostaglandin synthesis.Welsh mountain ewes were individually fed a control diet or a diet containing linseed (high in n-3 PUFA) for 6 weeks. To assess the impact of the diet during differe...

Increased dietary intake of polyunsaturated fatty acids (PUFAs) has been reported to be associated with a decreased incidence of cardiovascular disease. Increased dietary intake of polyunsaturated fatty acids (PUFAs) has been reported to be associated with a decreased incidence of cardiovascular disease. We have recently reported that ovarian steroid synthesis in ewes fed a diet high in n-3 PUFAs is significantly compromised1. Hence in this study we have assessed th...

Public health policy in recent years has favoured a reduction in saturated fats in favour of polyunsaturated fats due to the numerous health benefits of polyunsaturated fatty acids (PUFAs). Previous studies have demonstrated that PUFAs modulate gonadal steroidogenesis. We have therefore investigated the hypothesis that PUFAs modify steroidogenesis through affecting components of the cholesterol metabolising machinery, including steroidogenic acute regulatory (StAR) protein and...